Population genetic diversity in an Iraqi population and gene flow across the Arabian Peninsula.
Affiliation
University of DerbyMinistry of Interior of Qatar, Doha, Qatar
University of Central Lancashire
Issue Date
2020-09-17
Metadata
Show full item recordAbstract
Y-STRs have emerged as important forensic and population genetic markers for human identification and population differentiation studies. Therefore, population databases for these markers have been developed for almost all major populations around the world. The Iraqi population encompasses several ethnic groups that need to be genetically characterised and evaluated for possible substructures. Previous studies on the Iraqi population based on Y-STR markers were limited by a restricted number of markers. A larger database for Iraqi Arab population needed to be developed to help study and compare the population with other Middle Eastern populations. Twenty-three Y-STR loci included in the PowerPlex Y23 (Promega, Madison, WI, USA) were typed in 254 males from the Iraqi Arab population. Global and regional Y-STR analysis demonstrated regional genetic continuity among the populations of Iraq, the Arabian Peninsula and the Middle East. The Iraqi Arab haplotypes were used to allocate samples to their most likely haplogroups using Athey’s Haplogroup Predictor tool. Prediction indicated predominance (36.6%) of haplogroup J1 in Iraqi Arabs. The migration rate between other populations and the Iraqis was inferred using coalescence theory in the Migrate-n program. Y-STR data were used to test different out-of-Africa migration models as well as more recent migrations within the Arabian Peninsula. The migration models demonstrated that gene flow to Iraq began from East Africa, with the Levantine corridor the most probable passageway out of Africa. The data presented here will enrich our understanding of genetic diversity in the region and introduce a PowerPlex Y23 database to the forensic community.Citation
Lazim, H., Almohammed, E.K., Hadi, S. and Smith, J., (2020). 'Population genetic diversity in an Iraqi population and gene flow across the Arabian Peninsula'. Scientific reports, 10(1), pp.1-11.Publisher
NatureJournal
Scientific reportsDOI
10.1038/s41598-020-72283-1PubMed ID
32943725Additional Links
https://www.nature.com/articles/s41598-020-72283-1Type
ArticleLanguage
enSeries/Report no.
Article number: 15289 (2020)EISSN
2045-2322ae974a485f413a2113503eed53cd6c53
10.1038/s41598-020-72283-1
Scopus Count
Collections
The following license files are associated with this item:
- Creative Commons
Related articles
- Y-Chromosome haplotypes reveal relationships between populations of the Arabian Peninsula, North Africa and South Asia.
- Authors: Jones RJ, Tay GK, Mawart A, Alsafar H
- Issue date: 2017 Dec
- Y-Chromosome Haplogroups in the Bosnian-Herzegovinian Population Based on 23 Y-STR Loci.
- Authors: Doğan S, Ašić A, Doğan G, Besic L, Marjanovic D
- Issue date: 2016 Jul
- Prediction of the Y-Chromosome Haplogroups Within a Recently Settled Turkish Population in Sarajevo, Bosnia and Herzegovina.
- Authors: Doğan S, Doğan G, Ašić A, Besić L, Klimenta B, Hukić M, Turan Y, Primorac D, Marjanović D
- Issue date: 2016 Apr
- A comprehensive portrait of Y-STR diversity of Indian populations and comparison with 129 worldwide populations.
- Authors: Singh M, Sarkar A, Nandineni MR
- Issue date: 2018 Oct 18
- Highly discriminatory capacity of the PowerPlex(®) Y23 System for the study of isolated populations.
- Authors: Nuñez C, Baeta M, Fernández M, Zarrabeitia M, Martinez-Jarreta B, de Pancorbo MM
- Issue date: 2015 Jul