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    Acute liver failure in paracetamol overdose: management, transplantation and best practice

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    Name:
    Management of Paracetamol Overdose- ...
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    Authors
    Toplis, Emma
    Mortimore, Gerri
    Affiliation
    University of Derby
    Issue Date
    2020-07-02
    
    Metadata
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    Abstract
    In the United Kingdom the most common drug taken in overdose is paracetamol, which is recognised as a major cause of acute liver failure. However death rates from acute liver failure have fallen due to the rapid availability and accessibility of the antidote, acetylcysteine or N-acetylcysteine otherwise known as NAC. In this article the authors will critically evaluate the current literature surrounding the assessment and management of patients presenting with paracetamol overdose in order to improve their own clinical practise and promote best practice within their clinical team. This will include discussion of presentation, risk factors, treatment, complications and referral to specialist centres for transplant.
    Citation
    Mortimore, G., and Toplis, E. (2020). 'Acute liver failure in paracetamol overdose: management, transplantation and best practice'. Gastrointestinal Nursing, 18(6), pp.1-14.
    Publisher
    MA Healthcare
    Journal
    Gastrointestinal Nursing
    URI
    http://hdl.handle.net/10545/625045
    DOI
    10.12968/gasn.2020.18.Sup6.S34
    Additional Links
    https://www.magonlinelibrary.com/doi/abs/10.12968/gasn.2020.18.Sup6.S34
    Type
    Article
    Language
    en
    ISSN
    1479-5248
    EISSN
    2052-2835
    ae974a485f413a2113503eed53cd6c53
    10.12968/gasn.2020.18.Sup6.S34
    Scopus Count
    Collections
    School of Nursing and Professional Practice

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