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dc.contributor.authorStewart, Jill
dc.contributor.authorWalker, Thomas
dc.contributor.authorEldehini, Tarek
dc.contributor.authorHorner, Daniela Viramontes
dc.contributor.authorLucas, Bethany
dc.contributor.authorWhite, Kelly
dc.contributor.authorMuggleton, Andy
dc.contributor.authorSelby, Nicholas M
dc.contributor.authorTaal, Martin W
dc.contributor.authorStewart, Paul
dc.identifier.citationStewart, J., Walker, T., Eldehini, T., Viramontes Horner, D., Lucas, B., White, K., Muggleton, A., Selby, N. M., Taal, M. W., and Stewart, P. (2020). ‘A feasibility study of non-invasive Continuous Estimation of Brachial Pressure Derived from Arterial and Venous Lines During Dialysis’. IEEE Journal of Translational Engineering in Health and Medicine, 9, pp. 1-9.en_US
dc.description.abstractIntradialytic haemodynamic instability is a significant clinical problem, leading to end-organ ischaemia and contributing to morbidity and mortality in haemodialysis patients. Non-invasive continuous blood pressure monitoring is not part of routine practice but may aid detection and prevention of significant falls in blood pressure during dialysis. Brachial blood pressure is currently recorded intermittently during haemodialysis via a sphygmomanometer. Current methods of continuous non-invasive blood pressure monitoring tend to restrict movement, can be sensitive to external disturbances and patient movement, and can be uncomfortable for the wearer. Additionally, poor patient blood circulation can lead to unreliable measurements. In this study we performed an initial validation of a novel method and associated technology via a feasibility study to continuously estimate blood pressure using pressure sensors in the extra-corporeal dialysis circuit, which does not require any direct contact with the person receiving dialysis treatment.\\ The paper describes the development of the measurement system and subsequent \emph{in vivo} patient feasibility study with concurrent measurement validation by \emph{Finapres Nova} experimental physiological measurement device. We identify a mathematical function to describe the relationship between arterial line pressure and brachial artery BP, which is confirmed in the patient study. The methodology presented requires no interfacing to proprietery dialysis machine systems, no sensors to be attached to the patient directly, and to be robust to patient movement during treatment and also to the effects of the cyclical pressure waveforms induced by the hemodialysis pump. This represents a key enabling factor to the development of a practical continuous blood pressure monitoring device for dialysis patients.en_US
dc.description.sponsorshipThis is an output from the iTrend Intelligent Technologies for Renal Dialysis Programme funded by the MStart Charity and iTrend Ltd.en_US
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights2020 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other users, including reprinting/ republishing this material for advertising or promotional purposes, creating new collective works for resale or redistribution to servers or lists, or reuse of any copyrighted components of this work in other works.
dc.subjectBlood access pressure measurementen_US
dc.subjectcontinuous blood pressure measurementen_US
dc.subjectextracorporeal pressure sensorsen_US
dc.titleA feasibility study of non-invasive continuous estimation of brachial pressure derived from arterial and venous lines during dialysisen_US
dc.contributor.departmentUniversity of Derbyen_US
dc.contributor.departmentUniversity of Nottinghamen_US
dc.contributor.departmentRoyal Derby Hospitalen_US
dc.identifier.journalIEEE Journal of Translational Engineering in Health and Medicineen_US

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Attribution-NonCommercial-NoDerivatives 4.0 International
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 International