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dc.contributor.authorPick, HJ
dc.contributor.authorFaghy, Mark
dc.contributor.authorCresswell, G
dc.contributor.authorLim, WS
dc.contributor.authorBewick, T
dc.date.accessioned2019-02-22T13:59:49Z
dc.date.available2019-02-22T13:59:49Z
dc.date.issued2018-12-01
dc.identifier.citationPPick, H.J., Faghy, M.A., Cresswell, G., Lim, W.S. and Bewick, T., (2018). 'P25 Inspiratory muscle training (IMT) for adults discharged from hospital with community acquired pneumonia (CAP)–a feasibility study'. Thorax (73)4, pp. 1-2. DOI: 10.1136/thorax-2018-212555.183en_US
dc.identifier.issn0040-6376
dc.identifier.urihttp://hdl.handle.net/10545/623523
dc.description.abstractPatients report significant morbidity following community-acquired pneumonia (CAP); 70% report persistent symptoms and up to 50% impaired daily activity at 4 weeks post-discharge. Respiratory muscle weakness is one possible mechanism for delayed recovery. Inspiratory muscle training (IMT) increases strength and endurance of inspiratory muscles, with improvements in patient-reported outcomes in other conditions. To our knowledge IMT has not previously been investigated in CAP. To assess the tolerability of IMT in adults discharged from hospital with community-acquired pneumonia. Patients hospitalised with a diagnosis of CAP between February 2017 and March 2018 were eligible for inclusion and convenience sampling was used for participant selection. Participants received an IMT device (POWERbreath KHP2) following familiarisation. Training frequency (twice daily) and load (50% PImax) were fixed, however training volume was incremental during weeks 1–3 (10, 20, 30 breaths) and constant thereafter (30 breaths.) Participants were followed by combination of telephone and clinic visits for 9 weeks. Outcomes of interest were; utilisation of IMT device per protocol (defined as >94% training adherence), patient-reported IMT acceptability, and number of device-related side effects. Statistical analysis was conducted using Stata (version 15.1.) Twenty-two participants were recruited; 16 were male (72.7%), mean age was 55.2 years (range 27.9–77.3.) Participants completed IMT per protocol in 72.7% cases. One unrelated, unexpected serious adverse event (death) occurred during follow-up and 3 participants active at this time were stopped from further IMT by research sponsor pending investigation. Two participants were lost to follow-up. Side effects during IMT were reported on 15 occasions across 22 participants over a total 1183 training days. Reported side effects included chest pain (x2), cough (x1), dyspnoea (x4), and dizziness (x8). All side-effects were rated grade 1 and did not prevent participants from continuing training. Participant-reported IMT acceptability, defined by participants rating training as both ‘useful’ and ‘helpful’ at each follow-up contact, was 99.4%. Inspiratory muscle training appears to be safe, tolerable, and acceptable to patients following CAP. Distinguishing CAP related symptoms and device-related side effects is challenging in patients recovering following an acute infective illness. A clinical trial to determine efficacy is warranted.en_US
dc.description.sponsorshipNottingham University Hospitals Trusten_US
dc.language.isoenen_US
dc.relation.urlhttps://thorax.bmj.com/content/73/Suppl_4/A109.2en_US
dc.rights“This article has been accepted for publication in Thorax, 2018 following peer review, and the Version of Record can be accessed online at http://dx.doi.org/10.1136/thorax-2018-212555.183 “© Authors (or their employer(s)) OR “© BMJ Publishing Group Ltd” ( for assignments of BMJ Case Reports) “ <year>” [Add where a funder mandates: “Reuse of this manuscript version (excluding any databases, tables, diagrams, photographs and other images or illustrative material included where a another copyright owner is identified) is permitted strictly pursuant to the terms of the Creative Commons Attribution-Non Commercial 4.0 International (CC-BY-NC 4.0) http://creativecommons.org BMJ Authors Self-Archiving Policy, September 2018 https://creativecommons.org/licenses/by-nc/4.0/”]
dc.subjectInspiratory muscle trainingen_US
dc.subjectPneumoniaen_US
dc.titleInspiratory muscle training (IMT) for adults discharged from hospital with community acquired pneumonia (CAP) – a feasibility studyen_US
dc.typeArticleen_US
dc.typePresentationen_US
dc.identifier.eissn1468-3296
dc.contributor.departmentHuman Science Research Centre, University of Derbyen_US
dc.contributor.departmentNottingham University Hospitals NHS Trust, Nottingham, UKen_US
dc.contributor.departmentDerby Teaching Hospitals NHS Foundation Trust, Derby, UKen_US
dc.identifier.journalThoraxen_US
dcterms.dateAccepted2018-10-01
refterms.dateFOA2019-02-22T14:00:59Z


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