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    Genetic haemochromatosis: diagnosing and treating hereditary iron overload.

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    Authors
    Mortimore, Gerri cc
    Affiliation
    University of Derby
    Issue Date
    2017-12
    
    Metadata
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    Abstract
    Genetic haemochromatosis (GH) is the most common inherited genetic disorder in caucasians, affecting approximately 1 in every 200–250 people. It leads to an increased absorption and deposition of iron, and if it is untreated it can cause systemic iron overload in some patients. This iron overload can cause inflammation and tissue damage to multiple organs, with the potential to lead to heart disease, diabetes and cirrhosis of the liver. Despite being a common condition, it is thought to be under diagnosed. However, it is known that some patients with a diagnosis of GH will present with cirrhosis at a young age, while others are virtually asymptomatic. Symptoms can be generalised, and diagnosis is made on blood tests. Treatment for GH requires the removal of blood, known as venesection. Approximately 400–500mls are removed at a time, and this procedure can be undertaken weekly until ferritin levels are brought down to 50 µg/l or below.
    Citation
    Mortimore, G. (2017) 'Genetic haemochromatosis: diagnosing and treating hereditary iron overload', Gastrointestinal Nursing, 15 (Sup10):S16
    Publisher
    Mark Allen Group
    Journal
    Gastrointestinal Nursing
    URI
    http://hdl.handle.net/10545/622054
    DOI
    10.12968/gasn.2017.15.Sup10.S16
    Additional Links
    http://www.magonlinelibrary.com/doi/10.12968/gasn.2017.15.Sup10.S16
    Type
    Article
    Language
    en
    ISSN
    14795248
    20522835
    ae974a485f413a2113503eed53cd6c53
    10.12968/gasn.2017.15.Sup10.S16
    Scopus Count
    Collections
    School of Nursing and Professional Practice

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