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dc.contributor.authorMortimore, Gerri
dc.date.accessioned2017-06-23T14:35:09Z
dc.date.available2017-06-23T14:35:09Z
dc.date.issued2017-06
dc.identifier.citationMortimore, G. (2017) 'Primary biliary cholangitis: symptoms, diagnosis and treatment', Gastrointestinal Nursing, 15 (Sup5):S12en
dc.identifier.issn14795248
dc.identifier.doi10.12968/gasn.2017.15.Sup5.S12
dc.identifier.urihttp://hdl.handle.net/10545/621668
dc.description.abstractPrimary biliary cholangitis (PBC), previously known as primary biliary cirrhosis, is a chronic but progressive disease that, over many years, causes damage to bile ducts, leading to cholestasis and, in some patients, cirrhosis. The rate at which PBC progresses varies from person to person, but significant damage takes decades to occur. It predominately affects women aged 40–60 years with a female to male ratio of 9:1, but can affect anyone from the age of 20. There is no cure for PBC other than liver transplant, but medications can be given to slow down disease progression and for the treatment of symptoms. Health professionals should monitor for complications, including the development of osteoporosis, vitamin deficiencies and liver cirrhosis, which caries the associated complications of portal hypertension, varices and ascites.
dc.description.sponsorshipN/Aen
dc.language.isoenen
dc.publisherMark Allen Groupen
dc.relation.urlhttp://www.magonlinelibrary.com/doi/10.12968/gasn.2017.15.Sup5.S12en
dc.rightsArchived with thanks to Gastrointestinal Nursingen
dc.subjectDiagnosisen
dc.subjectCirrhoticsen
dc.subjectPrimary biliary cirrhosisen
dc.subjectPrimary biliary cholangitisen
dc.titlePrimary biliary cholangitis: symptoms, diagnosis and treatmenten
dc.typeArticleen
dc.identifier.eissn20522835
dc.contributor.departmentUniversity of Derbyen
dc.identifier.journalGastrointestinal Nursingen
html.description.abstractPrimary biliary cholangitis (PBC), previously known as primary biliary cirrhosis, is a chronic but progressive disease that, over many years, causes damage to bile ducts, leading to cholestasis and, in some patients, cirrhosis. The rate at which PBC progresses varies from person to person, but significant damage takes decades to occur. It predominately affects women aged 40–60 years with a female to male ratio of 9:1, but can affect anyone from the age of 20. There is no cure for PBC other than liver transplant, but medications can be given to slow down disease progression and for the treatment of symptoms. Health professionals should monitor for complications, including the development of osteoporosis, vitamin deficiencies and liver cirrhosis, which caries the associated complications of portal hypertension, varices and ascites.


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