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dc.contributor.authorTallis, Jason
dc.contributor.authorHiggins, Matthew F.
dc.contributor.authorCox, Val M.
dc.contributor.authorDuncan, Michael J.
dc.contributor.authorJames, Rob S.
dc.date.accessioned2016-12-15T09:21:27Z
dc.date.available2016-12-15T09:21:27Z
dc.date.issued2014-01
dc.identifier.citationTallis, J. et al (2014) 'Does a physiological concentration of taurine increase acute muscle power output, time to fatigue, and recovery in isolated mouse soleus (slow) muscle with or without the presence of caffeine?' Can. J. Physiol. Pharmacol. 92 (1):42-9en
dc.identifier.issn12057541
dc.identifier.pmid24383872
dc.identifier.doi10.1139/cjpp-2013-0195
dc.identifier.urihttp://hdl.handle.net/10545/621162
dc.description.abstractHigh concentrations of caffeine and taurine are key constituents of many ergogenic supplements ingested acutely to provide legal enhancements in athlete performance. Despite this, there is little evidence supporting the claims for the performance-enhancing effects of acute taurine supplementation. In-vitro models have demonstrated that a caffeine-induced muscle contracture can be further potentiated when combined with a high concentration of taurine. However, the high concentrations of caffeine used in previous research would be toxic for human consumption. Therefore, this study aimed to investigate whether a physiological dose of caffeine and taurine would directly potentiate skeletal muscle performance. Isolated mouse soleus muscle was used to examine the effects of physiological taurine (TAU), caffeine (CAF), and taurine-caffeine combined (TC) on (i) acute muscle power output; (ii) time to fatigue; and (iii) recovery from fatigue, compared with the untreated controls (CON). Treatment with TAU failed to elicit any significant difference in the measured parameters. Treatment with TC resulted in a significant increase in acute muscle power output and faster time to fatigue. The ergogenic benefit posed by TC was not different from the effects of caffeine alone, suggesting no acute ergogenic benefit of taurine.
dc.description.sponsorshipCoventry Universityen
dc.language.isoenen
dc.publisherNRC Research Pressen
dc.relation.urlhttps://www.ncbi.nlm.nih.gov/pubmed/24383872en
dc.rightsArchived with thanks to Canadian journal of physiology and pharmacologyen
dc.subjectErgogenic aiden
dc.subjectForceen
dc.subjectSkeletal muscleen
dc.subjectWork loopen
dc.subject.meshAnimals
dc.subject.meshCaffeine
dc.subject.meshFemale
dc.subject.meshIn Vitro Techniques
dc.subject.meshMice
dc.subject.meshMuscle Contraction
dc.subject.meshMuscle Fatigue
dc.subject.meshMuscle, Skeletal
dc.subject.meshTaurine
dc.titleDoes a physiological concentration of taurine increase acute muscle power output, time to fatigue, and recovery in isolated mouse soleus (slow) muscle with or without the presence of caffeine?en
dc.typeArticleen
dc.contributor.departmentUniversity of Derbyen
dc.identifier.journalCanadian journal of physiology and pharmacologyen
refterms.dateFOA2019-02-28T15:11:50Z
html.description.abstractHigh concentrations of caffeine and taurine are key constituents of many ergogenic supplements ingested acutely to provide legal enhancements in athlete performance. Despite this, there is little evidence supporting the claims for the performance-enhancing effects of acute taurine supplementation. In-vitro models have demonstrated that a caffeine-induced muscle contracture can be further potentiated when combined with a high concentration of taurine. However, the high concentrations of caffeine used in previous research would be toxic for human consumption. Therefore, this study aimed to investigate whether a physiological dose of caffeine and taurine would directly potentiate skeletal muscle performance. Isolated mouse soleus muscle was used to examine the effects of physiological taurine (TAU), caffeine (CAF), and taurine-caffeine combined (TC) on (i) acute muscle power output; (ii) time to fatigue; and (iii) recovery from fatigue, compared with the untreated controls (CON). Treatment with TAU failed to elicit any significant difference in the measured parameters. Treatment with TC resulted in a significant increase in acute muscle power output and faster time to fatigue. The ergogenic benefit posed by TC was not different from the effects of caffeine alone, suggesting no acute ergogenic benefit of taurine.


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