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dc.contributor.authorDanookdharree, Urvashi
dc.contributor.authorLe, Huirong
dc.contributor.authorHandy, Richard
dc.contributor.authorTredwin, Christopher
dc.date.accessioned2016-12-02T12:38:18Z
dc.date.available2016-12-02T12:38:18Z
dc.date.issued2015-09-16
dc.identifier.citationDanookdharree, U. (2015) 'Antibacterial coating made of strongly adhered nanosilver to titania nanotubes for dental implants', Proceedings of the British Society for Oral and Dental Research (BSODR) Annual Meeting, Cardiff, 14-16 Sepen
dc.identifier.urihttp://hdl.handle.net/10545/621104
dc.description.abstractObjectives: An antibacterial and biocompatible coating on Ti-6Al-4V alloy was synthesised. A method of making the antibacterial effect long term, without any acute release of silver from a dental implant, on insertion was devised.Methods: Titania nanotubes were grown on Ti-6Al-4V alloy using anodisation in the presence of phosphate and fluoride ions. Following alkali treatment of the latter surface, silver nanoparticles were chemically reduced on the nanotubes. The latter surface was then characterised using high resolution electron microscopy (SEM) in association with energy dispersive X-Ray Spectroscopy (EDS) and Raman Spectroscopy. A silver release test was performed. Following a toxicity test in the presence of Human Osteoblast Cells, the biocompatibility of the coating would be assessed.Results: Initially, titania nanotubes with diameter of c. 100 nm were formed following the deposition of silver nanoparticles (10-25nm) on the outer and inner walls. The chemical structure of the nanoparticles was confirmed by Raman Spectroscopy and EDS. The results also highlighted the different bonding attaching the nanosilver to the walls. Subsequently a very low amount of silver was released from the coating during the beginning of the silver release test confirming a good adherence between the nanosilver and the nanotubes. The low leaching was expected to reduce the toxicity of the implant in general and it was confirmed by growth of human osteoblast cells on the coating.Conclusions: The strong adhesion of silver nanoparticles validated the fact that the coating on titanium alloy can prevent an acute release of silver as such having the possibility of having a long term antibacterial effects. This work gave rise to a novel method of synthesising an antibacterial coating for dental implants.
dc.language.isoenen
dc.publisherInternational Association for Dental Researchen
dc.relation.urlhttp://www.bsodr.org.uk/meetings/cardiff-2015/en
dc.relation.urlhttps://live.blueskybroadcast.com/bsb/client/_new_default.asp?action=HOME&Client=404900en
dc.relation.urlhttp://www.bsodr.org.uk/meetings/cardiff-2015/BSODR-2015-Final-programme.pdfen
dc.subjectDental materialsen
dc.subjectTitanium alloyen
dc.subjectCarbon nanotubesen
dc.subjectChemical reductionen
dc.titleAntibacterial coating made of strongly adhered nanosilver to titania nanotubes for dental implantsen
dc.typeMeetings and Proceedingsen
dc.contributor.departmentUniversity of Plymouthen
dc.contributor.departmentUniversity of Derbyen
dc.identifier.journalProceedings of the British Society for Oral and Dental Research (BSODR) Annual Meetingen
html.description.abstractObjectives: An antibacterial and biocompatible coating on Ti-6Al-4V alloy was synthesised. A method of making the antibacterial effect long term, without any acute release of silver from a dental implant, on insertion was devised.Methods: Titania nanotubes were grown on Ti-6Al-4V alloy using anodisation in the presence of phosphate and fluoride ions. Following alkali treatment of the latter surface, silver nanoparticles were chemically reduced on the nanotubes. The latter surface was then characterised using high resolution electron microscopy (SEM) in association with energy dispersive X-Ray Spectroscopy (EDS) and Raman Spectroscopy. A silver release test was performed. Following a toxicity test in the presence of Human Osteoblast Cells, the biocompatibility of the coating would be assessed.Results: Initially, titania nanotubes with diameter of c. 100 nm were formed following the deposition of silver nanoparticles (10-25nm) on the outer and inner walls. The chemical structure of the nanoparticles was confirmed by Raman Spectroscopy and EDS. The results also highlighted the different bonding attaching the nanosilver to the walls. Subsequently a very low amount of silver was released from the coating during the beginning of the silver release test confirming a good adherence between the nanosilver and the nanotubes. The low leaching was expected to reduce the toxicity of the implant in general and it was confirmed by growth of human osteoblast cells on the coating.Conclusions: The strong adhesion of silver nanoparticles validated the fact that the coating on titanium alloy can prevent an acute release of silver as such having the possibility of having a long term antibacterial effects. This work gave rise to a novel method of synthesising an antibacterial coating for dental implants.


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