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    Analysis of HEp-2 images using MD-LBP and MAD-bagging

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    Authors
    Schaefer, Gerald
    Doshi, Niraj P.
    Zhu, Shao Ying
    Hu, Qinghua
    Affiliation
    Loughborough University
    University of Derby
    Issue Date
    2014-08
    
    Metadata
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    Abstract
    Indirect immunofluorescence imaging is employed to identify antinuclear antibodies in HEp-2 cells which founds the basis for diagnosing autoimmune diseases and other important pathological conditions involving the immune system. Six categories of HEp-2 cells are generally considered, namely homogeneous, fine speckled, coarse speckled, nucleolar, cyto-plasmic, and centromere cells. Typically, this categorisation is performed manually by an expert and is hence both time consuming and subjective. In this paper, we present a method for automatically classifiying HEp-2 cells using texture information in conjunction with a suitable classification system. In particular, we extract multidimensional local binary pattern (MD-LBP) texture features to characterise the cell area. These then form the input for a classification stage, for which we employ a margin distribution based bagging pruning (MAD-Bagging) classifier ensemble. We evaluate our algorithm on the ICPR 2012 HEp-2 contest benchmark dataset, and demonstrate it to give excellent performance, superior to all algorithms that were entered in the competition.
    Citation
    Schaefer, G. et al (2014) 'Analysis of HEp-2 images using MD-LBP and MAD-bagging', Proceedings of the 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), Chicago: USA, 26-30 August.
    Publisher
    IEEE
    Journal
    Proceedings of the 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
    URI
    http://hdl.handle.net/10545/620920
    DOI
    10.1109/EMBC.2014.6944562
    Additional Links
    http://ieeexplore.ieee.org/document/6944562/
    http://embc.embs.org/2014/
    Type
    Meetings and Proceedings
    Language
    en
    ISBN
    9781424479290
    ae974a485f413a2113503eed53cd6c53
    10.1109/EMBC.2014.6944562
    Scopus Count
    Collections
    Department of Electronics, Computing & Maths

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