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Increased knowledge of the effects of smoking and second-hand smoke encourages smoke-free homes.Objective: To establish the drivers for smoke-free homes among current daily smokers. Design: A cross-sectional study employing interviews (adults) and self-completed surveys (schoolchildren). Sample: Children aged 12 and 14 in schools in four cities in China, India, Mexico and England.Adults in the community. Measurements: Knowledge, attitude, beliefs and behaviour relevant to second-hand smoke in home. Intervention: None. Results: A total of 8994 adults and 14,756 children were surveyed. Knowledge of some of the effects of tobacco is high, but other effects are poorly understood in all cities.