Hdl Handle:
http://hdl.handle.net/10545/621808
Title:
Prospective audit of liver biopsy practice: Is bigger better?
Authors:
Li, Ka Kit; Mortimore, Gerri; Jackson, Michelle; Semeraro, David; Clarke, Dominic; Freeman, Jan G.; Austin, Andrew
Abstract:
Background: Percutaneous liver biopsy remains an important toolin the diagnosis and staging of chronic liver disease. For reliableand reproducible interpretation, a specimen containing a minimum of six portal tracts and ideally more than ten is required.There is often reluctance to use wider bore needles because ofpotentially higher complication rates. Aims: To compare the ad-equacy of samples obtained using two different biopsy needles.Patients and Methods: Data was collected prospectively for 128ultrasound-sited percutaneous biopsies for chronic liver diseaseover a 10 month period using a proforma. Results: Indications forbiopsy were alcoholic liver disease (21%), NAFLD (21%), HCV(14%), HBV (8%), haemachromatosis (10%), autoimmune hepatitis(8%), other (22%). There were no serious adverse events in eithergroup. Biopsy characteristics are compared in Table 1. Data areexpressed as mean (CI) or median (range) and compared using ttest, Mann-Whitney U test or Chi-squared. Conclusions: Liverbiopsy samples obtained with a 15G Menghini needle are superiorto those obtained using an 18G Trucut needle. The latter are ofteninadequate for assessment using accepted criteria.
Affiliation:
Royal Derby Hospital
Citation:
Li, K. et al (2006) 'Prospective audit of liver biopsy practice: Is bigger better?', Hepatology, Vol. 44, Suppl. S1, p. 377A
Publisher:
Wiley
Journal:
Hepatology
Issue Date:
Oct-2006
URI:
http://hdl.handle.net/10545/621808
Additional Links:
http://aasldpubs.onlinelibrary.wiley.com/hub/issue/10.1002/hep.v44:1%2B/
Type:
Article
Language:
en
ISSN:
2709139
Sponsors:
N/A
Appears in Collections:
Department of Health Care Practice

Full metadata record

DC FieldValue Language
dc.contributor.authorLi, Ka Kiten
dc.contributor.authorMortimore, Gerrien
dc.contributor.authorJackson, Michelleen
dc.contributor.authorSemeraro, Daviden
dc.contributor.authorClarke, Dominicen
dc.contributor.authorFreeman, Jan G.en
dc.contributor.authorAustin, Andrewen
dc.date.accessioned2017-08-08T11:47:56Z-
dc.date.available2017-08-08T11:47:56Z-
dc.date.issued2006-10-
dc.identifier.citationLi, K. et al (2006) 'Prospective audit of liver biopsy practice: Is bigger better?', Hepatology, Vol. 44, Suppl. S1, p. 377Aen
dc.identifier.issn2709139-
dc.identifier.urihttp://hdl.handle.net/10545/621808-
dc.description.abstractBackground: Percutaneous liver biopsy remains an important toolin the diagnosis and staging of chronic liver disease. For reliableand reproducible interpretation, a specimen containing a minimum of six portal tracts and ideally more than ten is required.There is often reluctance to use wider bore needles because ofpotentially higher complication rates. Aims: To compare the ad-equacy of samples obtained using two different biopsy needles.Patients and Methods: Data was collected prospectively for 128ultrasound-sited percutaneous biopsies for chronic liver diseaseover a 10 month period using a proforma. Results: Indications forbiopsy were alcoholic liver disease (21%), NAFLD (21%), HCV(14%), HBV (8%), haemachromatosis (10%), autoimmune hepatitis(8%), other (22%). There were no serious adverse events in eithergroup. Biopsy characteristics are compared in Table 1. Data areexpressed as mean (CI) or median (range) and compared using ttest, Mann-Whitney U test or Chi-squared. Conclusions: Liverbiopsy samples obtained with a 15G Menghini needle are superiorto those obtained using an 18G Trucut needle. The latter are ofteninadequate for assessment using accepted criteria.en
dc.description.sponsorshipN/Aen
dc.language.isoenen
dc.publisherWileyen
dc.relation.urlhttp://aasldpubs.onlinelibrary.wiley.com/hub/issue/10.1002/hep.v44:1%2B/en
dc.subjectLiver biopsyen
dc.subjectLiver samplesen
dc.subjectHistopathogyen
dc.titleProspective audit of liver biopsy practice: Is bigger better?en
dc.typeArticleen
dc.contributor.departmentRoyal Derby Hospitalen
dc.identifier.journalHepatologyen
All Items in UDORA are protected by copyright, with all rights reserved, unless otherwise indicated.