On the importance of the microbiome and pathobiome in coral health and disease

Hdl Handle:
http://hdl.handle.net/10545/621344
Title:
On the importance of the microbiome and pathobiome in coral health and disease
Authors:
Sweet, Michael J. ( 0000-0003-4983-8333 ) ; Bulling, Mark T.
Abstract:
The term “microbiome” was first coined in 1988 and given the definition of a characteristic microbial community occupying a reasonably well defined habitat which has distinct physio-chemical properties. A more recent term has also emerged, taking this one step further and focusing on diseases in host organisms. The “pathobiome” breaks down the concept of “one pathogen = one disease” and highlights the role of the microbiome, more specifically certain members within the microbiome, in causing pathogenesis. The development of next generation sequencing has allowed large data sets to be amassed describing the microbial communities of many organisms and the field of coral biology is no exception. However, the choices made in the analytical process and the interpretation of these data can significantly affect the outcome and the overall conclusions drawn. In this review we explore the implications of these difficulties, as well as highlighting analytical tools developed in other research fields (such as network analysis) which hold substantial potential in helping to develop a deeper understanding of the role of the microbiome in disease in corals. We also make the case that standardization of methods will substantially improve the collective gain in knowledge across research groups.
Affiliation:
University of Derby
Citation:
Sweet, M. J. and Bulling, M. T. (2017) 'On the Importance of the Microbiome and Pathobiome in Coral Health and Disease', Frontiers in Marine Science, 4, doi: 10.3389/fmars.2017.00009
Publisher:
Frontiers
Journal:
Frontiers in Marine Science
Issue Date:
20-Jan-2017
URI:
http://hdl.handle.net/10545/621344
DOI:
10.3389/fmars.2017.00009
Additional Links:
http://journal.frontiersin.org/article/10.3389/fmars.2017.00009/full
Type:
Article
Language:
en
ISSN:
22967745
Sponsors:
N/A
Appears in Collections:
Environmental Sustainability Research Centre

Full metadata record

DC FieldValue Language
dc.contributor.authorSweet, Michael J.en
dc.contributor.authorBulling, Mark T.en
dc.date.accessioned2017-02-06T16:01:42Z-
dc.date.available2017-02-06T16:01:42Z-
dc.date.issued2017-01-20-
dc.identifier.citationSweet, M. J. and Bulling, M. T. (2017) 'On the Importance of the Microbiome and Pathobiome in Coral Health and Disease', Frontiers in Marine Science, 4, doi: 10.3389/fmars.2017.00009en
dc.identifier.issn22967745-
dc.identifier.doi10.3389/fmars.2017.00009-
dc.identifier.urihttp://hdl.handle.net/10545/621344-
dc.description.abstractThe term “microbiome” was first coined in 1988 and given the definition of a characteristic microbial community occupying a reasonably well defined habitat which has distinct physio-chemical properties. A more recent term has also emerged, taking this one step further and focusing on diseases in host organisms. The “pathobiome” breaks down the concept of “one pathogen = one disease” and highlights the role of the microbiome, more specifically certain members within the microbiome, in causing pathogenesis. The development of next generation sequencing has allowed large data sets to be amassed describing the microbial communities of many organisms and the field of coral biology is no exception. However, the choices made in the analytical process and the interpretation of these data can significantly affect the outcome and the overall conclusions drawn. In this review we explore the implications of these difficulties, as well as highlighting analytical tools developed in other research fields (such as network analysis) which hold substantial potential in helping to develop a deeper understanding of the role of the microbiome in disease in corals. We also make the case that standardization of methods will substantially improve the collective gain in knowledge across research groups.en
dc.description.sponsorshipN/Aen
dc.language.isoenen
dc.publisherFrontiersen
dc.relation.urlhttp://journal.frontiersin.org/article/10.3389/fmars.2017.00009/fullen
dc.rightsArchived with thanks to Frontiers in Marine Scienceen
dc.subjectMicroorganismsen
dc.subjectDiseaseen
dc.subjectGeneen
dc.subjectVibrioen
dc.subjectMacro-ecologyen
dc.subjectNetwork analysisen
dc.subjectMicrobiologyen
dc.subjectBacteriaen
dc.titleOn the importance of the microbiome and pathobiome in coral health and diseaseen
dc.typeArticleen
dc.contributor.departmentUniversity of Derbyen
dc.identifier.journalFrontiers in Marine Scienceen
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