Does a physiological concentration of taurine increase acute muscle power output, time to fatigue, and recovery in isolated mouse soleus (slow) muscle with or without the presence of caffeine?

2.50
Hdl Handle:
http://hdl.handle.net/10545/621162
Title:
Does a physiological concentration of taurine increase acute muscle power output, time to fatigue, and recovery in isolated mouse soleus (slow) muscle with or without the presence of caffeine?
Authors:
Tallis, Jason; Higgins, Matthew F.; Cox, Val M.; Duncan, Michael J. ( 0000-0002-2016-6580 ) ; James, Rob S. ( 0000-0002-3969-8261 )
Abstract:
High concentrations of caffeine and taurine are key constituents of many ergogenic supplements ingested acutely to provide legal enhancements in athlete performance. Despite this, there is little evidence supporting the claims for the performance-enhancing effects of acute taurine supplementation. In-vitro models have demonstrated that a caffeine-induced muscle contracture can be further potentiated when combined with a high concentration of taurine. However, the high concentrations of caffeine used in previous research would be toxic for human consumption. Therefore, this study aimed to investigate whether a physiological dose of caffeine and taurine would directly potentiate skeletal muscle performance. Isolated mouse soleus muscle was used to examine the effects of physiological taurine (TAU), caffeine (CAF), and taurine-caffeine combined (TC) on (i) acute muscle power output; (ii) time to fatigue; and (iii) recovery from fatigue, compared with the untreated controls (CON). Treatment with TAU failed to elicit any significant difference in the measured parameters. Treatment with TC resulted in a significant increase in acute muscle power output and faster time to fatigue. The ergogenic benefit posed by TC was not different from the effects of caffeine alone, suggesting no acute ergogenic benefit of taurine.
Affiliation:
University of Derby
Citation:
Tallis, J. et al (2014) 'Does a physiological concentration of taurine increase acute muscle power output, time to fatigue, and recovery in isolated mouse soleus (slow) muscle with or without the presence of caffeine?' Can. J. Physiol. Pharmacol. 92 (1):42-9
Publisher:
NRC Research Press
Journal:
Canadian journal of physiology and pharmacology
Issue Date:
Jan-2014
URI:
http://hdl.handle.net/10545/621162
DOI:
10.1139/cjpp-2013-0195
PubMed ID:
24383872
Additional Links:
https://www.ncbi.nlm.nih.gov/pubmed/24383872
Type:
Article
Language:
en
ISSN:
12057541
Sponsors:
Coventry University
Appears in Collections:
Department of Life Sciences

Full metadata record

DC FieldValue Language
dc.contributor.authorTallis, Jasonen
dc.contributor.authorHiggins, Matthew F.en
dc.contributor.authorCox, Val M.en
dc.contributor.authorDuncan, Michael J.en
dc.contributor.authorJames, Rob S.en
dc.date.accessioned2016-12-15T09:21:27Z-
dc.date.available2016-12-15T09:21:27Z-
dc.date.issued2014-01-
dc.identifier.citationTallis, J. et al (2014) 'Does a physiological concentration of taurine increase acute muscle power output, time to fatigue, and recovery in isolated mouse soleus (slow) muscle with or without the presence of caffeine?' Can. J. Physiol. Pharmacol. 92 (1):42-9en
dc.identifier.issn12057541-
dc.identifier.pmid24383872-
dc.identifier.doi10.1139/cjpp-2013-0195-
dc.identifier.urihttp://hdl.handle.net/10545/621162-
dc.description.abstractHigh concentrations of caffeine and taurine are key constituents of many ergogenic supplements ingested acutely to provide legal enhancements in athlete performance. Despite this, there is little evidence supporting the claims for the performance-enhancing effects of acute taurine supplementation. In-vitro models have demonstrated that a caffeine-induced muscle contracture can be further potentiated when combined with a high concentration of taurine. However, the high concentrations of caffeine used in previous research would be toxic for human consumption. Therefore, this study aimed to investigate whether a physiological dose of caffeine and taurine would directly potentiate skeletal muscle performance. Isolated mouse soleus muscle was used to examine the effects of physiological taurine (TAU), caffeine (CAF), and taurine-caffeine combined (TC) on (i) acute muscle power output; (ii) time to fatigue; and (iii) recovery from fatigue, compared with the untreated controls (CON). Treatment with TAU failed to elicit any significant difference in the measured parameters. Treatment with TC resulted in a significant increase in acute muscle power output and faster time to fatigue. The ergogenic benefit posed by TC was not different from the effects of caffeine alone, suggesting no acute ergogenic benefit of taurine.en
dc.description.sponsorshipCoventry Universityen
dc.language.isoenen
dc.publisherNRC Research Pressen
dc.relation.urlhttps://www.ncbi.nlm.nih.gov/pubmed/24383872en
dc.rightsArchived with thanks to Canadian journal of physiology and pharmacologyen
dc.subjectErgogenic aiden
dc.subjectForceen
dc.subjectSkeletal muscleen
dc.subjectWork loopen
dc.subject.meshAnimals-
dc.subject.meshCaffeine-
dc.subject.meshFemale-
dc.subject.meshIn Vitro Techniques-
dc.subject.meshMice-
dc.subject.meshMuscle Contraction-
dc.subject.meshMuscle Fatigue-
dc.subject.meshMuscle, Skeletal-
dc.subject.meshTaurine-
dc.titleDoes a physiological concentration of taurine increase acute muscle power output, time to fatigue, and recovery in isolated mouse soleus (slow) muscle with or without the presence of caffeine?en
dc.typeArticleen
dc.contributor.departmentUniversity of Derbyen
dc.identifier.journalCanadian journal of physiology and pharmacologyen
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