Increased gravitational force reveals the mechanical, resonant nature of physiological tremor

2.50
Hdl Handle:
http://hdl.handle.net/10545/619128
Title:
Increased gravitational force reveals the mechanical, resonant nature of physiological tremor
Authors:
Lakie, M.; Vernooij, C. A.; Osler, Callum J.; Stevenson, A. T.; Scott, J. P. R.; Reynolds, Raymond Francis
Abstract:
Human physiological hand tremor has a resonant component. Proof of this is that its frequency can be modified by adding mass. However, adding mass also increases the load which must be supported. The necessary force requires muscular contraction which will change motor output and is likely to increase limb stiffness. The increased stiffness will partly offset the effect of the increased mass and this can lead to the erroneous conclusion that factors other than resonance are involved in determining tremor frequency. Using a human centrifuge to increase head-to-foot gravitational field strength, we were able to control for the increased effort by increasing force without changing mass. This revealed that the peak frequency of human hand tremor is 99% predictable on the basis of a resonant mechanism. We ask what, if anything, the peak frequency of physiological tremor can reveal about the operation of the nervous system.
Affiliation:
University of Birmingham, UK; Aix-Marseille Universite, Marseille, France; University of Derby, UK; QinetiQ, Farnborough, UK; King’s College London, UK; Wyle GmbH, Koln, Germany
Citation:
Lakie, M. et al (2015) 'Increased gravitational force reveals the mechanical, resonant nature of physiological tremor', The Journal of Physiology, 593 (19):4411
Publisher:
Wiley
Journal:
The Journal of Physiology
Issue Date:
10-Jan-2015
URI:
http://hdl.handle.net/10545/619128
DOI:
10.1113/JP270464
Additional Links:
http://doi.wiley.com/10.1113/JP270464
Type:
Article
Language:
en
ISSN:
223751
Sponsors:
This work was funded by a BBSRC Industry Interchange Award to J.P.R.S. and R.F.R. C.J.O. was funded by BBSRC grant BB/I00579X/1. C.A.V. was funded by A∗Midex (Aix-Marseille Initiative of Excellence)
Appears in Collections:
Department of Life Sciences

Full metadata record

DC FieldValue Language
dc.contributor.authorLakie, M.en
dc.contributor.authorVernooij, C. A.en
dc.contributor.authorOsler, Callum J.en
dc.contributor.authorStevenson, A. T.en
dc.contributor.authorScott, J. P. R.en
dc.contributor.authorReynolds, Raymond Francisen
dc.date.accessioned2016-08-31T13:15:18Z-
dc.date.available2016-08-31T13:15:18Z-
dc.date.issued2015-01-10-
dc.identifier.citationLakie, M. et al (2015) 'Increased gravitational force reveals the mechanical, resonant nature of physiological tremor', The Journal of Physiology, 593 (19):4411en
dc.identifier.issn223751-
dc.identifier.doi10.1113/JP270464-
dc.identifier.urihttp://hdl.handle.net/10545/619128-
dc.description.abstractHuman physiological hand tremor has a resonant component. Proof of this is that its frequency can be modified by adding mass. However, adding mass also increases the load which must be supported. The necessary force requires muscular contraction which will change motor output and is likely to increase limb stiffness. The increased stiffness will partly offset the effect of the increased mass and this can lead to the erroneous conclusion that factors other than resonance are involved in determining tremor frequency. Using a human centrifuge to increase head-to-foot gravitational field strength, we were able to control for the increased effort by increasing force without changing mass. This revealed that the peak frequency of human hand tremor is 99% predictable on the basis of a resonant mechanism. We ask what, if anything, the peak frequency of physiological tremor can reveal about the operation of the nervous system.en
dc.description.sponsorshipThis work was funded by a BBSRC Industry Interchange Award to J.P.R.S. and R.F.R. C.J.O. was funded by BBSRC grant BB/I00579X/1. C.A.V. was funded by A∗Midex (Aix-Marseille Initiative of Excellence)en
dc.language.isoenen
dc.publisherWileyen
dc.relation.urlhttp://doi.wiley.com/10.1113/JP270464en
dc.rightsArchived with thanks to The Journal of Physiologyen
dc.subjectTremoren
dc.titleIncreased gravitational force reveals the mechanical, resonant nature of physiological tremoren
dc.typeArticleen
dc.contributor.departmentUniversity of Birmingham, UKen
dc.contributor.departmentAix-Marseille Universite, Marseille, Franceen
dc.contributor.departmentUniversity of Derby, UKen
dc.contributor.departmentQinetiQ, Farnborough, UKen
dc.contributor.departmentKing’s College London, UKen
dc.contributor.departmentWyle GmbH, Koln, Germanyen
dc.identifier.journalThe Journal of Physiologyen
dc.contributor.institutionSchool of Sport, Exercise and Rehabilitation Sciences; University of Birmingham; UK-
dc.contributor.institutionSchool of Sport, Exercise and Rehabilitation Sciences; University of Birmingham; UK-
dc.contributor.institutionSchool of Sport, Exercise and Rehabilitation Sciences; University of Birmingham; UK-
dc.contributor.institutionQinetiQ Aircrew Systems, Air Division; QinetiQ; Farnborough UK-
dc.contributor.institutionWyle GmbH; Köln Germany-
dc.contributor.institutionSchool of Sport, Exercise and Rehabilitation Sciences; University of Birmingham; UK-
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