Recreational 3,4-methylenedioxy-N-methylamphetamine (MDMA) or ‘ecstasy’ and self-focused compassion: Preliminary steps in the development of a therapeutic psychopharmacology of contemplative practices

2.50
Hdl Handle:
http://hdl.handle.net/10545/621749
Title:
Recreational 3,4-methylenedioxy-N-methylamphetamine (MDMA) or ‘ecstasy’ and self-focused compassion: Preliminary steps in the development of a therapeutic psychopharmacology of contemplative practices
Authors:
Kamboj, Sunjeev K; Kilford, Emma J.; Minchin, Stephanie; Moss, Abigail; Lawn, Will; Das, Ravi K.; Falconer, Caroline J.; Gilbert, Paul ( 0000-0001-8431-9892 ) ; Curran, H Valerie; Freeman, Tom P.
Abstract:
3,4-methylenedioxy-N-methylamphetamine (MDMA) produces diverse pro-social effects. Cognitive training methods rooted in Eastern contemplative practices also produce these effects through the development of a compassionate mindset. Given this similarity, we propose that one potential mechanism of action of MDMA in psychotherapy is through enhancing effects on intrapersonal attitudes (i.e. pro-social attitudes towards the self). We provide a preliminary test of this idea. Recreational MDMA (ecstasy)-users were tested on two occasions, having consumed or not consumed ecstasy. Selfcritical and self-compassionate responses to self-threatening scenarios were assessed before (T1) and after (T2) ecstasyuse (or no use), and then after compassionate imagery (T3). Moderating roles of dispositional self-criticism and avoidant attachment were examined. Separately, compassionate imagery and ecstasy produced similar sociotropic effects as well as increases and reductions in self-compassion and self-criticism respectively. Higher attachment-related avoidance was associated with additive effects of compassionate imagery and ecstasy on self-compassion. Findings were in line with MDMA’s neuropharmacological profile, its phenomenological effects and proposed adjunctive use in psychotherapy. However, although conditions were balanced, the experiment was non-blind and MDMA dose/purity was not determined. Controlled studies with pharmaceutically pure MDMA are still needed to test these effects rigorously.
Affiliation:
University College London; University of Derby
Citation:
Kamboj, S. K. et al (2015) 'Recreational 3,4-methylenedioxy-N-methylamphetamine (MDMA) or ‘ecstasy’ and self-focused compassion: Preliminary steps in the development of a therapeutic psychopharmacology of contemplative practices', Journal of Psychopharmacology, 29 (9):961
Publisher:
Sage
Journal:
Journal of Psychopharmacology
Issue Date:
18-May-2015
URI:
http://hdl.handle.net/10545/621749
DOI:
10.1177/0269881115587143
Additional Links:
http://journals.sagepub.com/doi/10.1177/0269881115587143
Type:
Article
Language:
en
ISSN:
02698811
EISSN:
14617285
Sponsors:
N/A
Appears in Collections:
Centre for Psychological Research

Full metadata record

DC FieldValue Language
dc.contributor.authorKamboj, Sunjeev Ken
dc.contributor.authorKilford, Emma J.en
dc.contributor.authorMinchin, Stephanieen
dc.contributor.authorMoss, Abigailen
dc.contributor.authorLawn, Willen
dc.contributor.authorDas, Ravi K.en
dc.contributor.authorFalconer, Caroline J.en
dc.contributor.authorGilbert, Paulen
dc.contributor.authorCurran, H Valerieen
dc.contributor.authorFreeman, Tom P.en
dc.date.accessioned2017-07-14T16:08:55Z-
dc.date.available2017-07-14T16:08:55Z-
dc.date.issued2015-05-18-
dc.identifier.citationKamboj, S. K. et al (2015) 'Recreational 3,4-methylenedioxy-N-methylamphetamine (MDMA) or ‘ecstasy’ and self-focused compassion: Preliminary steps in the development of a therapeutic psychopharmacology of contemplative practices', Journal of Psychopharmacology, 29 (9):961en
dc.identifier.issn02698811-
dc.identifier.doi10.1177/0269881115587143-
dc.identifier.urihttp://hdl.handle.net/10545/621749-
dc.description.abstract3,4-methylenedioxy-N-methylamphetamine (MDMA) produces diverse pro-social effects. Cognitive training methods rooted in Eastern contemplative practices also produce these effects through the development of a compassionate mindset. Given this similarity, we propose that one potential mechanism of action of MDMA in psychotherapy is through enhancing effects on intrapersonal attitudes (i.e. pro-social attitudes towards the self). We provide a preliminary test of this idea. Recreational MDMA (ecstasy)-users were tested on two occasions, having consumed or not consumed ecstasy. Selfcritical and self-compassionate responses to self-threatening scenarios were assessed before (T1) and after (T2) ecstasyuse (or no use), and then after compassionate imagery (T3). Moderating roles of dispositional self-criticism and avoidant attachment were examined. Separately, compassionate imagery and ecstasy produced similar sociotropic effects as well as increases and reductions in self-compassion and self-criticism respectively. Higher attachment-related avoidance was associated with additive effects of compassionate imagery and ecstasy on self-compassion. Findings were in line with MDMA’s neuropharmacological profile, its phenomenological effects and proposed adjunctive use in psychotherapy. However, although conditions were balanced, the experiment was non-blind and MDMA dose/purity was not determined. Controlled studies with pharmaceutically pure MDMA are still needed to test these effects rigorously.en
dc.description.sponsorshipN/Aen
dc.language.isoenen
dc.publisherSageen
dc.relation.urlhttp://journals.sagepub.com/doi/10.1177/0269881115587143en
dc.rightsArchived with thanks to Journal of Psychopharmacologyen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectMDMAen
dc.subjectCompassion-focused therapyen
dc.subjectCompassionen
dc.subjectPsychotherapyen
dc.subjectSelf-criticismen
dc.titleRecreational 3,4-methylenedioxy-N-methylamphetamine (MDMA) or ‘ecstasy’ and self-focused compassion: Preliminary steps in the development of a therapeutic psychopharmacology of contemplative practicesen
dc.typeArticleen
dc.identifier.eissn14617285-
dc.contributor.departmentUniversity College Londonen
dc.contributor.departmentUniversity of Derbyen
dc.identifier.journalJournal of Psychopharmacologyen
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