The role of Eag and HERG channels in cell proliferation and apoptotic cell death in SK-OV-3 ovarian cancer cell line.

2.50
Hdl Handle:
http://hdl.handle.net/10545/225603
Title:
The role of Eag and HERG channels in cell proliferation and apoptotic cell death in SK-OV-3 ovarian cancer cell line.
Authors:
Asher, Viren; Warren, Averil; Shaw, Robert; Sowter, Heidi M. ( 0000-0002-1408-1900 ) ; Bali, Anish; Khan, Raheela
Abstract:
The voltage gated potassium (K+) channels Eag and HERG have been implicated in the pathogenesis of various cancers, through association with cell cycle changes and programmed cell death. The role of these channels in the onset and progression of ovarian cancer is unknown. An understanding of mechanism by which Eag and HERG channels affect cell proliferation in ovarian cancer cells is required and therefore we investigated their role in cell proliferation and their effect on the cell cycle and apoptosis of ovarian cancer cells.
Affiliation:
Royal Derby Hospital, School of Graduate Entry Medicine and Health; University of Derby, Faculty of Education, Health and Science
Citation:
The role of Eag and HERG channels in cell proliferation and apoptotic cell death in SK-OV-3 ovarian cancer cell line. 2011, 11:6 Cancer Cell Int.
Journal:
Cancer cell international
Issue Date:
Mar-2011
URI:
http://hdl.handle.net/10545/225603
DOI:
10.1186/1475-2867-11-6
PubMed ID:
21392380
Type:
Article
Language:
en
ISSN:
1475-2867
Appears in Collections:
Biological Sciences Research Group

Full metadata record

DC FieldValue Language
dc.contributor.authorAsher, Virenen_GB
dc.contributor.authorWarren, Averilen_GB
dc.contributor.authorShaw, Roberten_GB
dc.contributor.authorSowter, Heidi M.en_GB
dc.contributor.authorBali, Anishen_GB
dc.contributor.authorKhan, Raheelaen_GB
dc.date.accessioned2012-05-23T14:50:16Z-
dc.date.available2012-05-23T14:50:16Z-
dc.date.issued2011-03-
dc.identifier.citationThe role of Eag and HERG channels in cell proliferation and apoptotic cell death in SK-OV-3 ovarian cancer cell line. 2011, 11:6 Cancer Cell Int.en_GB
dc.identifier.issn1475-2867-
dc.identifier.pmid21392380-
dc.identifier.doi10.1186/1475-2867-11-6-
dc.identifier.urihttp://hdl.handle.net/10545/225603-
dc.description.abstractThe voltage gated potassium (K+) channels Eag and HERG have been implicated in the pathogenesis of various cancers, through association with cell cycle changes and programmed cell death. The role of these channels in the onset and progression of ovarian cancer is unknown. An understanding of mechanism by which Eag and HERG channels affect cell proliferation in ovarian cancer cells is required and therefore we investigated their role in cell proliferation and their effect on the cell cycle and apoptosis of ovarian cancer cells.en_GB
dc.language.isoenen
dc.rightsArchived with thanks to Cancer cell internationalen_GB
dc.subjectOvarian cancer-
dc.subjectPotassium channels-
dc.subjectEag1-
dc.titleThe role of Eag and HERG channels in cell proliferation and apoptotic cell death in SK-OV-3 ovarian cancer cell line.en
dc.typeArticleen
dc.contributor.departmentRoyal Derby Hospital, School of Graduate Entry Medicine and Healthen_GB
dc.contributor.departmentUniversity of Derby, Faculty of Education, Health and Scienceen_GB
dc.identifier.journalCancer cell internationalen_GB

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